Aurora A Monoclonal Antibody (35C1), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Aurora A
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
Aik; Airk; AIRK1; Ark1; ARK-1; AU019385; AURA; AURAK; AURKA; Aurora 2; aurora A; Aurora A Kinase; Aurora family kinase 1; Aurora kinase A; aurora/IP; aurora/IPL1-like kinase; Aurora/IPL1-related kinase 1; AURORA2; Aurora-A; aurora-related kinase 1; AW539821; Ayk1; BOS_13320; Breast tumor-amplified kinase; BTAK; CR956640.2; EC 2.7.11.1; hARK1; IAK; Iak1; Ipl1- and aurora-related kinase 1; IPL1-related kinase; MGC34538; OTTHUMP00000031341; OTTHUMP00000166072; PPP1R47; protein phosphatase 1, regulatory subunit 47; ratAurA; RP5-1167H4.6; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; Stk15; Stk6; STK7
Gene Symbols
AURKA
Isotype
IgG2b
Purification Method
Protein A
Product Type
Antibody
Clone
35C1
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
O14965
Gene ID (Entrez)
6790
Immunogen
This antibody was raised against full-length recombinant human Aurora A protein.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
AURKA
Related Products
Description
- Aurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation
- Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal
- Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen
- Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines
- Multiple transcript variants encoding the same protein have been found for this gene
- Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.