MyoD Monoclonal Antibody (5F11), Active Motif™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MyoD
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
AI503393; BHLHC1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; Myoblast determination protein 1 homolog; MYOD; Myod1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; Myogenic factor 3; PUM
Gene Symbols
MYOD1
Isotype
IgG2a
Purification Method
Protein G
Product Type
Antibody
Clone
5F11
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Human, Mouse
Gene Accession No.
P10085, P15172
Gene ID (Entrez)
17927, 4654
Immunogen
This MyoD antibody was raised against a recombinant protein corresponding to full-length mouse MyoD.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
MYOD1
Related Products
Description
- Description The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells
- It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells
- The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif
- Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD
- These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).