Myc-Tag Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™
Mouse Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Myc-Tag
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P01106
Gene ID (Entrez)
4609
Immunogen
This antibody was raised against a peptide corresponding to amino acids 410-419 of human c-Myc (EQkLISEEDL).
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
MYC
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias
46-0603; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; MYCC; myc-related translation/localization regulatory factor; Proto-oncogene c-Myc; R95025; R950-25; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols
MYC
Isotype
IgG2a
Purification Method
Protein A
Product Type
Antibody
Related Products
Description
- Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation
- The encoded protein forms a heterodimer with the related transcription factor MAX
- This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes
- Amplification of this gene is frequently observed in numerous human cancers
- Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients
- There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.