LIN28A Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
LIN28A
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
Q8K3Y3, Q9H9Z2
Gene ID (Entrez)
79727, 83557
Immunogen
This LIN28A antibody was raised against a peptide derived from the C-terminal region of human LIN28A.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
LIN28A
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
AL024421; CSDD1; ENSMUSG00000070700; FLJ12457; Gm10299; lin28; lin-28; lin-28 homolog A; lin-28 homolog A (C. elegans); Lin28a; Lin-28A; Protein lin-28 homolog A; RGD1566408; RNA-binding protein lin-28; sb:cb650; si:ch211-232d9.4; similar to RNA-binding protein LIN-28; testis expressed gene 17; Testis-expressed protein 17; Tex17; ZCCHC1; zgc:55584; Zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1
Gene Symbols
LIN28A
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C
- elegans
- The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases
- Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts
- More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.