7188946

SALL4 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SALL4

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Mouse

Gene Accession No.

Q8BX22

Gene ID (Entrez)

99377

Immunogen

This SALL4 antibody was raised against a synthetic peptide derived from the N-terminus of human SALL4.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

SALL4

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

5730441M18Rik; AA407717; AL022809; AW536104; C330011P20Rik; C78083; C78563; CH242-152A8.2; dJ1112F19.1; DRRS; HSAL4; SALL4; sal-like 4; sal-like 4 (Drosophila); Sal-like protein 4; spalt like transcription factor 4; spalt-like transcription factor 4; Tex20; Zinc finger protein 797; Zinc finger protein SALL4; ZNF797

Gene Symbols

SALL4

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • Sall4 protein is encoded by the Sall4 gene located on chromosome 20 in humans and belongs to the Spalt-like protein family
  • It plays an important role in somatic stem cell maintenance and is studied as a stem cell biomarker
  • It is a zinc finger transcription factor that is upregulated during development and shown to interact with Oct4 and Sox2
  • It also forms a complex with Nanog to maintain the pluripotency of Embryonic Stem cells (ESCs)
  • Several current research studies focus on its function as an oncogene and tumor biomarker
  • Some of the reported target genes of Sall4 include p53, Bmi-1, Bcl2 and XIAP.