Cholera Toxin Beta Antibody - BSA Free, Novus Biologicals™
Rabbit Polyclonal Antibody has been used in 2 publications
Manufacturer: Fischer Scientific
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Antigen
Cholera Toxin Beta
Dilution
ELISA 1:100-1:2000, Immunohistochemistry-Frozen, Immunodiffusion
Classification
Polyclonal
Form
Purified
Regulatory Status
RUO
Formulation
Phosphate buffered saline with 0.1% Sodium Azide
Immunogen
Purified choleragenoid
Primary or Secondary
Primary
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration
4 mg/mL
Applications
ELISA, Immunodiffusion, Immunohistochemistry (Frozen)
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Bacteria
Gene Alias
Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, toxB, VC1456
Isotype
IgG
Purification Method
IgG purified
Test Specificity
NB100-63067 is specific for the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. This antibody immunoprecipitates cholera toxin in gel techniques.
Related Products
Description
- Cholera Toxin Beta Polyclonal specifically detects Cholera Toxin Beta in Bacteria samples
- It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Frozen, Immunodiffusion.