7240797
HAMP Monoclonal Antibody (D7), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
HAMP
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
HAMP; Hamp1; HEPC; Hepc1; Hepc20; Hepc25; Hepcidin; hepcidin antimicrobial peptide; hepcidin antimicrobial peptide 1; Hepcidin-20; Hepcidin-25; HFE2B; LEAP1; LEAP-1; liver-expressed antimicrobial peptide 1; PLTR; Putative liver tumor regressor; UNQ487/PRO1003
Gene Symbols
HAMP
Isotype
IgG2b κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
D7
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P81172
Gene ID (Entrez)
57817
Immunogen
Ser25-Thr84 (Accession P81172), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
HAMP
Related Products
Description
- HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption
- The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures
- These peptides exhibit antimicrobial activity.