7240864
Amylin Monoclonal Antibody (C2), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Amylin
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
Gene Symbols
IAPP
Isotype
IgG2a κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
C2
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P10997
Gene ID (Entrez)
3375
Immunogen
Synthetic peptide, which is conjugated to OVA. Lys34-Val50 (Accession P10997), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
IAPP
Related Products
Description
- The target peptide sequence is KCNTATCATQRLANFLV
- Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma
- While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish
- Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.