CXCL12 alpha (SDF-1 alpha) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CXCL12 alpha (SDF-1 alpha)
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Goat
Target Species
Mouse
Gene Accession No.
P40224
Gene ID (Entrez)
20315
Immunogen
E.coli-derived, 7.9 kDa Recombinant Murine SDF-1alpha (CXCL12)
Purification Method
Antigen affinity chromatography
Gene
CXCL12
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1a; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1a; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
Gene Symbols
CXCL12
Primary or Secondary
Primary
Content And Storage
-20°C
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Description
- AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
- Preparation: Produced from sera of goats immunized with highly pure recombinant Murine SDF-1alpha (CXCL12)
- Anti-Murine SDF-1alpha (CXCL12)-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Murine SDF-1alpha by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine SDF-1alpha (500-P164G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine SDF-1alpha
- Western Blot: To detect Murine SDF-1alpha by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Murine SDF-1alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P164GBT-1MG will be provided as 2 x 500 μg CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family
- This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer
- Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections
- Multiple transcript variants encoding different isoforms have been found for this gene.