89-114-204

APP (phospho S730), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-114-204-Each-of-1 In Stock ₹ 57,138.00

89-114-204 - Each of 1

₹ 57,138.00

In Stock

Quantity

1

Base Price: ₹ 57,138.00

GST (18%): ₹ 10,284.84

Total Price: ₹ 67,422.84

Antigen

APP

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of APP.

Formulation

In PBS (0.09% sodium azide)

Gene Accession No.

NP_000475;P05067

Gene Symbols

APP

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S730 of human APP.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Gene

APP

Gene Alias

AAA/ABETA/ABPP/AD1/APPI/CTFgamma/CVAP/PN2

Host Species

Rabbit

Purification Method

Protein G purification

Regulatory Status

RUO

Gene ID (Entrez)

351

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • Description This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides
  • Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease
  • Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy)
  • Multiple transcript variants encoding several different isoforms have been found for this gene
  • [provided by RefSeq