89-118-429

ATM (phospho S1981), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-118-429-Each-of-1 In Stock ₹ 57,138.00

89-118-429 - Each of 1

₹ 57,138.00

In Stock

Quantity

1

Base Price: ₹ 57,138.00

GST (18%): ₹ 10,284.84

Total Price: ₹ 67,422.84

Antigen

ATM

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ATM.

Formulation

In PBS (0.09% sodium azide)

Gene Accession No.

NP_000042;Q13315

Gene Symbols

ATM

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S1981 of human ATM.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Dot Blot, ELISA

Conjugate

Unconjugated

Dilution

Dot Blot (1:500) The optimal working dilution should be determined by the end user.

Gene

ATM

Gene Alias

AT1/ATA/ATC/ATD/ATDC/ATE/DKFZp781A0353/MGC74674/TEL1/TELO1

Host Species

Rabbit

Purification Method

Protein A purification

Regulatory Status

RUO

Gene ID (Entrez)

472

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene belongs to the PI3/PI4-kinase family
  • This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1
  • This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability
  • Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder
  • Two transcript variants encoding different isoforms have been found for this gene
  • [provided by RefSeq