89-956-741

CAV1 (phospho Y14) Rabbit anti-Human, Mouse, Rabbit, Polyclonal , Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-956-741-Each-of-1 In Stock ₹ 55,803.00

89-956-741 - Each of 1

₹ 55,803.00

In Stock

Quantity

1

Base Price: ₹ 55,803.00

GST (18%): ₹ 10,044.54

Total Price: ₹ 65,847.54

Antigen

CAV1 (phospho Y14)

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CAV1.

Formulation

In PBS (without Mg2+and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Symbols

CAV1

Immunogen

A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y14 of human CAV1.

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

CAV1 (phospho Y14) polyclonal antibody detects endogenous level of CAV1 only when phosphorylated at tyrosine 14.

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

Immunofluorescence, Western Blot

Conjugate

Unconjugated

Dilution

Immunofluorescence (1:100-1:200) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene Alias

BSCL3/CAV/CGL3/MSTP085/VIP21

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

857

Target Species

Human, Mouse, Rabbit

Form

Liquid

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Description

  • The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types
  • The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression
  • The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade
  • CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex
  • By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene
  • [provided by RefSeq]