ABN1698MI

MilliporeSigma™ Rabbit anti-Aspa/Nur7, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1698MI-Each-of-1 In Stock ₹ 42,716.44

ABN1698MI - Each of 1

₹ 42,716.44

In Stock

Quantity

1

Base Price: ₹ 42,716.44

GST (18%): ₹ 7,688.959

Total Price: ₹ 50,405.399

Antigen

Aspa/Nur7

Classification

Polyclonal

Gene Accession No.

Q8R3P0

Host Species

Rabbit

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Purified

Applications

Immunohistochemistry, Western Blot

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

Aspa

Immunogen

N-terminally his-tagged full-length recombinant mouse Aspa/Nur7.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_075602

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

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Description

  • Specifically detects Aspa/Nur7 in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Western Blotting Aspartoacylase (EC 3.5.1.15; UniProt Q8R3P0; also known as Acy-2, Aminoacylase-2, Nur-7) is encoded by the Aspa (also known as Acy2) gene (Gene ID 11484) in murine species
  • Aspartoacylase catalyzes the deacetylation of N-acetylaspartate (NAA) to generate free acetate in the central nervous system (CNS)
  • Mutations in the ASPA gene cause the autosomal recessive neurodegenerative Canavan disease (CD) that results in inadequate lipid/myelin synthesis during development
  • Immunohistochemical staining reveals that aspartoacylase colocalizes with the oligodendrocyte marker CC1 throughout the brain, indicating its role in myelination.