ABS1610MI

MilliporeSigma™ Rabbit anti-ERLIN-2/SPFH2, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABS1610MI-Each-of-1 In Stock ₹ 37,825.00

ABS1610MI - Each of 1

₹ 37,825.00

In Stock

Quantity

1

Base Price: ₹ 37,825.00

GST (18%): ₹ 6,808.50

Total Price: ₹ 44,633.50

Antigen

ERLIN-2/SPFH2

Classification

Polyclonal

Gene Accession No.

B5DEH2

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Rat

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Formulation

Purified rabbit polyclonal antibody in buffer containing 155mM NaCl, 50mM Tris-HCl Ph 7.4 with 0.05% sodium azide and 10% glycerol.

Gene Symbols

Erlin2; Spfh2

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of rat ERLIN-2/SPFH2.

Quantity

100 μL

Research Discipline

Signaling

Gene ID (Entrez)

NP_001099558

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

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Description

  • Specifically detects ERLIN-2/SPFH2 in Human, Rat samples, and it is validated for Immunocytochemistry, Immunoprecipitation, Western Blotting Erlin-2 (UniProt B5DEH2; also known as Endoplasmic reticulum lipid raft-associated protein 2, SPFH domain-containing protein 2, SPFH domain family member 2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) is encoded by the Erlin2 (also known as RGD1309010, Spfh2) gene (Gene ID 290823) in rat species
  • Erlin2 (Spfh2) and the highly homologous Erlin1 (Spfh1) are ER proteins that hetero-oligomerize into a large complex of ∼2 MDa
  • The erlin1/2 complex associates with inositol 1,4,5-trisphosphate (IP(3)) receptors on ER membrane and is responsible for recruiting RNF170 upon IP(3) receptor activation for subsequent ubiquitination-dependent receptor downregulation.