APP4552

Parkin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APP4552-Each-of-1 In Stock ₹ 46,502.50

APP4552 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Parkin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRKN

Gene Alias

AAN12155.1; AR-JP; CG10523; CG10523-PB; CG10523-PC; Dmel\CG10523; Dmel_CG10523; Dpark; dParkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; park; park1; PARK2; Parkin; parkin 2; parkin F; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; Prkn; SD01679

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5071

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O60260

Gene Symbols

PRKN

Immunogen

Internal sequence of the 52 kDa Parkin human protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-4552 detects Parkin in human samples
  • PA1-4552 has been successfully used in Western blotting and immunoprecipitation procedures
  • By Western blot, this antibody detects a ∽52 kDa protein representing Parkin in HEK cells stably expressing the protein
  • PA1-4552 immunizing peptide corresponds to an internal sequence of the 52 kDa Parkin human protein
  • Maintain antibody at 4oC for up to 3 months
  • For long term storage, store at -20oC, avoiding freeze/thaw cycles
  • The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation
  • Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease
  • Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms
  • Additional splice variants of this gene have been described but currently lack transcript support.