BDB559954
CD220 Mouse anti-Human, Unlabeled, Clone: 3B6/IR, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB559954-Each-of-1 | In Stock | ₹ 14,596.00 |
BDB559954 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,596.00
GST (18%): ₹ 2,627.28
Total Price: ₹ 17,223.28
Antigen
CD220
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Insulin Receptor, Insulin R
Host Species
Mouse
Quantity
0.1 mg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
3B6/IR
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Reacts with insulin receptor (IR), a glycoprotein composed of two extracellular α-subunits (130 kDa) and two transmembrane β-subunits (95 kDa)
- It is expressed on human hematopoietic and non-hematopoietic cells, but unlike the insulin-like growth factor receptor (IGF-IR), which is ubiquitous, the insulin receptor is restricted to major target tissues of insulin action
- Upon binding insulin, the IR subunits form a heterotetramer of two α and two β subunits resulting in autophosphorylation and activation of the tyrosine kinase activity of the receptor
- This ligand-receptor interaction is important in regulating cell metabolism and growth
- 3B6/IR monoclonal antibody reacts similarly to anti-human IR α, clone 47-9, an α-subunit antibody.