BDB561194

CD64 Mouse anti-Human, PerCP-Cy5.5, Clone: 10.1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561194-Each-of-1 In Stock ₹ 19,135.00

BDB561194 - Each of 1

₹ 19,135.00

In Stock

Quantity

1

Base Price: ₹ 19,135.00

GST (18%): ₹ 3,444.30

Total Price: ₹ 22,579.30

Antigen

CD64

Classification

Monoclonal

Conjugate

PerCP-Cyanine5.5

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

10.1

Description

FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses
  • CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells
  • CD64 associates with a signaling FcRγ homodimer to form the functional high affinity FcγRI complex
  • CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.