BDB563643
Blimp-1 Rat anti-Mouse, Alexa Fluor 647, Clone: 5E7., BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563643-Each-of-1 | In Stock | ₹ 27,367.50 |
BDB563643 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,367.50
GST (18%): ₹ 4,926.15
Total Price: ₹ 32,293.65
Antigen
Blimp-1
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Prdm1; PR domain zinc finger protein 1; Blimp1; PRDI-BF1; ZNFPR1A1
Immunogen
Mouse Blimp-1 Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
5E7.
Conjugate
Alexa Fluor 647
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The 5E7 monoclonal antibody specifically binds to mouse B lymphocyte-induced maturation protein 1 (Blimp-1)
- Blimp-1 is a 98 kDa zinc finger-containing protein that is encoded by the Prdm1 gene and functions as a transcriptional repressor
- Blimp-1 is essential for regulating the terminal differentiation of activated B cells into plasma cells
- In this process, Blimp-1 suppresses genes involved in B cell proliferation, such as Myc and Bcl6
- It controls other genes, such as Xbp1, that are required for upregulating the plasma cell’s protein synthesis machinery which is essential for antibody production and secretion
- Blimp-1 is an important regulator in other cell types as well
- It functions in the regulation of T cell activation and homeostasis and NK cell maturation
- Blimp-1 is expressed in activated T cells and can function to inhibit IL-2 production while enhancing the differentiation and expression of several molecules produced by effector T cells.