BDB563665
CD294 (CRTH2) Rat anti-Human, PE, Clone: BM16, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563665-Each-of-1 | In Stock | ₹ 28,124.00 |
BDB563665 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,124.00
GST (18%): ₹ 5,062.32
Total Price: ₹ 33,186.32
Antigen
CD294 (CRTH2)
Classification
Monoclonal
Conjugate
PE
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
BM16
Description
CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44
Immunogen
Human CRTH2 Transfected Cell Line
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The BM16 monoclonal antibody specifically binds to CD294
- CD294 is encoded by PTGDR2 (Prostaglandin D2 receptor 2) and is also known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), GPR44 (G protein-coupled receptor 44), DL1R, and DP2
- CD294 is a member of the G protein-coupled leukocyte chemoattractant receptor family
- CD294 is expressed on Th2 cells and type-2 innate lymphoid cells (ILC2), but not Th1 type cells
- CD294 is detectable on CD4+ T cells in fresh PBMC but not on B cells and NK cells
- CD294 is also expressed on peripheral blood basophils and eosinophils, suggesting its involvement allergic reactions
- Phenotypic analysis of CD4+ T cells expressing CRTH2 demonstrated that they were also CD45RA-negative and CD45RO+ and CD25+
- These cells produce Th2- but little or no Th1-type cytokines upon stimulation with PMA and Ionomycin.