BDB563671
CD71 Mouse anti-Human, APC-H7, Clone: M-A712, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563671-Each-of-1 | In Stock | ₹ 21,983.00 |
BDB563671 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,983.00
GST (18%): ₹ 3,956.94
Total Price: ₹ 25,939.94
Antigen
CD71
Classification
Monoclonal
Conjugate
APC-H7
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
M-A712
Description
TFR; TFRC; Trfr; TfR1; Transferrin receptor protein 1
Immunogen
T-CLL and Jurkat Cells
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR)
- This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers
- CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells
- CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens
- Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin
- After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface.