BDB563769

CD71 Mouse anti-Human, Alexa Fluor 700, Clone: M-A712, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563769-Each-of-1 In Stock ₹ 20,915.00

BDB563769 - Each of 1

₹ 20,915.00

In Stock

Quantity

1

Base Price: ₹ 20,915.00

GST (18%): ₹ 3,764.70

Total Price: ₹ 24,679.70

Antigen

CD71

Classification

Monoclonal

Conjugate

Alexa Fluor 700

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

M-A712

Description

TFR; TFRC; Trfr; TfR1; Transferrin receptor protein 1

Immunogen

T-CLL and Jurkat Cells

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR)
  • This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers
  • CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells
  • CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens
  • Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin
  • After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface.