BDB564256
CD273 Mouse anti-Human, PerCP-Cy5.5, Clone: MIH18, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564256-Each-of-1 | In Stock | ₹ 33,464.00 |
BDB564256 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,464.00
GST (18%): ₹ 6,023.52
Total Price: ₹ 39,487.52
Antigen
CD273
Classification
Monoclonal
Conjugate
PerCP-Cyanine5.5
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen
Human CD273 Transfected Cell Line
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
MIH18
Description
PD-1 ligand 2; PD-L2; B7-DC; PDCD1LG2; PDCD1 ligand 2; PDCD1L2; PDL2; Btdc
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The MIH18 monoclonal antibody specifically binds to CD273 which is also known as the Programmed Death Ligand 2 (PD-L2) and B7-DC
- CD273 is a type 1 transmembrane glycoprotein member of the B7 family and Ig superfamily
- CD273 serves as a ligand for CD279, the Programmed Death 1 (PD-1) receptor
- CD273 is expressed by dendritic cells, activated monocytes, medullary thymic epithelial cells, placental trophoblasts, and myocardial endothelium
- CD273 can function as a coinhibitor of T cell functions by acting through CD279
- Monoclonal antibodies that block the CD273 and CD279 interaction result in enhanced T cell proliferation and cytokine production
- Thus, CD273 can play an important role in regulating T cell responses
- Clone MIH18 is reportedly a blocking antibody.