BDB565149

CD86 Mouse anti-Human, APC-R700, Clone: 2331 (FUN-1), BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565149-Each-of-1 In Stock ₹ 32,351.50

BDB565149 - Each of 1

₹ 32,351.50

In Stock

Quantity

1

Base Price: ₹ 32,351.50

GST (18%): ₹ 5,823.27

Total Price: ₹ 38,174.77

Antigen

CD86

Classification

Monoclonal

Conjugate

APC-R700

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.

Immunogen

Human HBL-1 Cell Line

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

2331 (FUN-1)

Description

B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1 κ

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Description

  • The 2331 (FUN-1) monoclonal antibody specifically recognizes a 75 kDa transmembrane cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes, dendritic cells and activated B cells
  • Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (Anti-CD86) antibodies specifically recognize the same molecule, they react with different epitopes
  • CD86 is a ligand for CD28 and CTLA-4 and plays an important role in costimulation of T cells in primary immune response
  • The 2331 (FUN-1) antibody blocks the costimulatory activity of CD86 when tested in functional studies
  • This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
  • APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
  • This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).