BDB565181
CD28 Mouse anti-Human, APC-R700, Clone: CD28, 2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565181-Each-of-1 | In Stock | ₹ 17,266.00 |
BDB565181 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,266.00
GST (18%): ₹ 3,107.88
Total Price: ₹ 20,373.88
Antigen
CD28
Classification
Monoclonal
Conjugate
APC-R700
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen
Human CD28 Transfected Cell Line
Quantity
50 Tests
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
CD28, 2
Description
CD28 antigen; T44; Tp44; TP44
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Gene ID (Entrez)
940
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The CD28.2 monoclonal antibody specifically binds to CD28, a 44 kDa homodimeric transmembrane glycoprotein present on most mature T cells, thymocytes and plasma cells
- CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in T cell-B cell interactions
- It has been suggested that CD28 initiates and regulates a separate and distinct signal transduction pathway from those stimulated by the TCR complex
- Additionally, it has been reported that CD28 antibody clones vary in their ability to stimulate T cells to produce IL-2 and increase intracellular Ca2+ concentration
- This finding suggests the existence of functionally distinct subregions on the CD28 molecule
- CD28.2 has been demonstrated to bind to the same molecule as clone L293, another CD28 mAb, and has been reported to induce Ca2+ influx in Jurkat T cells
- This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
- APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
- This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).