BDB565195
CD117 Mouse anti-Human, APC-R700, Clone: YB5.B8, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565195-Each-of-1 | In Stock | ₹ 32,218.00 |
BDB565195 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,218.00
GST (18%): ₹ 5,799.24
Total Price: ₹ 38,017.24
Antigen
CD117
Classification
Monoclonal
Conjugate
APC-R700
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.
Immunogen
Acute myelocytic leukemia blasts
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
YB5.B8
Description
KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The YB5.B8 monoclonal antibody specifically binds to CD117, which is also known as c-Kit, or Stem cell factor Receptor (SCFR)
- CD117 is a ∽145 kDa type I transmembrane glycoprotein with tyrosine kinase activity
- CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes
- CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF), or mast cell growth factor (MGF)
- The interaction of CD117 and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development
- The ability of the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial
- This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
- APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
- This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).