CD137 Recombinant Human Monoclonal Antibody (1H7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549969-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA549969 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
CD137
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
Q07011
Gene Symbols
TNFRSF9
Immunogen
Recombinant Human TNFRSF9 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Neutralization
Clone
1H7
Conjugate
Unconjugated
Gene
TNFRSF9
Gene Alias
4 1 BB, 41BB, 4-1BB, 4-1BB ligand receptor, A930040I11Rik, AA408498, AI325004, Cd137, CD137 antigen, CDw137, EGK_00183, homolog of mouse 4-1BB, ILA, induced by lymphocyte activation (ILA), interleukin-activated receptor, homolog of mouse Ly63, Ly63, receptor protein 4-1BB, s4 1 BB, s4 1BB, s41BB, sCD137, secreted CD137 antigen, soluble 4 1 BB, soluble 4 1BB, soluble 41BB, soluble CD137, T cell antigen ILA, T-cell antigen 4-1BB, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNF receptor superfamily member 9, TNFRSF9, Tumor necrosis factor receptor superfamily member 9, tumor necrosis factor receptor superfamily, member 9
Host Species
Human
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3604
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG2
Related Products
Description
- CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells
- Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells
- CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development
- Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival
- Soluble forms of CD137 may provide negative control mechanism for some immune responses.