FEMA550228

TM4SF1 Recombinant Human Monoclonal Antibody (6B3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550228-Each-of-1 In Stock ₹ 37,202.00

FEMA550228 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

TM4SF1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

P30408

Gene Symbols

TM4SF1

Immunogen

Recombinant Human TM4SF1 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Neutralization

Clone

6B3

Conjugate

Unconjugated

Gene

TM4SF1

Gene Alias

12A8 target antigen, H-L6, L6, L6 antigen, M3S1, Membrane component chromosome 3 surface marker 1, membrane component chromosome 3 surface marker 1 homolog, membrane component, chromosome 3, surface marker 1, membrane component, surface marker 1, TAAL6, TM4SF1, transmembrane 4 L six family member 1, transmembrane 4 L6 family member 1, transmembrane 4 superfamily member 1, tumor-associated antigen L6

Host Species

Human

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4071

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG1

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Description

  • TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family
  • Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility
  • TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers
  • Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.