FEMA549977

C5AR1 Recombinant Human Monoclonal Antibody (3A7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549977-Each-of-1 In Stock ₹ 37,202.00

FEMA549977 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

C5AR1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

P21730

Gene Symbols

C5AR1

Immunogen

Recombinant Human C5AR1 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Neutralization

Clone

3A7

Conjugate

Unconjugated

Gene

C5AR1

Gene Alias

anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1

Host Species

Human

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

728

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG1

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Description

  • CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
  • C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
  • CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
  • Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
  • CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
  • Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.