FEMA550133

EGR2 Recombinant Rabbit Monoclonal Antibody (27C3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550133-Each-of-1 In Stock ₹ 37,202.00

FEMA550133 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

EGR2

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P08152, P11161

Gene Symbols

Egr2

Immunogen

A synthesized peptide derived from Human EGR2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Clone

27C3

Conjugate

Unconjugated

Gene

Egr2

Gene Alias

AT591, CMT1D, CMT4E, DKFZp686J1957, E3 SUMO-protein ligase EGR2, E3 SUMO-protein transferase ERG2, early growth response 2, early growth response protein 2, Egr2, Egr-2, FLJ1454, FLJ14547, Krox20, Krox-20, Krox-20 homolog, KROX-20, Drosophila, homolog (early growth response-2), NGF1-B, OTTHUMP00000062133, Zfp-25, Zfp-6, Zinc finger protein Krox-20

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13654, 1959

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • The EGR2 gene provides instructions for making a protein called early growth response 2, which is part of the early growth response family of proteins
  • These proteins bind to specific areas of DNA and help control the activity of particular genes
  • On the basis of this action, the proteins are referred to as transcription factors
  • The early growth response 2 protein activates several genes that are involved in the formation and maintenance of myelin, the fatty substance that covers and protects nerve cells
  • Myelin promotes the efficient transmission of nerve impulses
  • If myelin is lost (demyelination) or its structure is disrupted, the transmission of nerve impulses is impaired
  • Mutations in the EGR2 gene can cause two forms of Charcot-Marie-Tooth disease, type 1D or type 4E (sometimes called congenital hypomyelinating neuropathy) or a severe form of type 1D (sometimes called Dejerine-Sottas syndrome) that begins during infancy or early childhood.