LAMP2 Recombinant Rabbit Monoclonal Antibody (23G11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550152-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550152 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
LAMP2
Classification
Recombinant Monoclonal
Concentration
1.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P13473
Gene Symbols
LAMP2
Immunogen
A synthesized peptide derived from Human LAMP2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
23G11
Conjugate
Unconjugated
Gene
LAMP2
Gene Alias
CD107 antigen-like family member B, CD107b, EGK_20887, Igp96, Lamp II, LAMP2, LAMP-2, LAMP-2 Isoform 2A, LAMP-2 Variant A, Lamp-2a, Lamp-2b, Lamp-2c, LAMPB, LGP110, LGP-110, LGP-96, LGP-B, lysosomal associated membrane protein 2, lysosomal membrane glycoprotein 2, lysosomal membrane glycoprotein type B, lysosomal-associated membrane protein 2, lysosome-associated membrane glycoprotein 2, lysosome-associated membrane protein 2, Mac3, RP23-193O17.2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3920
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Description LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins
- LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome
- Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide
- Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa
- LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
- LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy
- LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
- The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C
- LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane
- The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation
- LAMP2 deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danon’s disease).