FEMA550241

UBE2C Recombinant Mouse Monoclonal Antibody (22E1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550241-Each-of-1 In Stock ₹ 37,202.00

FEMA550241 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

UBE2C

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

O00762

Gene Symbols

UBE2C

Immunogen

Recombinant Human UBE2C protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

22E1

Conjugate

Unconjugated

Gene

UBE2C

Gene Alias

(E3-independent) E2 ubiquitin-conjugating enzyme C, 1110015A16Rik, cyclin-selective ubiquitin carrier protein, D2Ertd695e, dJ447F3.2, E2 ubiquitin-conjugating enzyme C, mitotic-specific ubiquitin-conjugating enzyme, RP3-447F3.1, ubcH10, UBE2C, Ubiquitin carrier protein C, ubiquitin conjugating enzyme E2 C, ubiquitin conjugating enzyme E2C, ubiquitin-conjugating enzyme E2 C, ubiquitin-conjugating enzyme E2C, ubiquitin-protein ligase C

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11065

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • This gene encodes a member of the E2 ubiquitin-conjugating enzyme family
  • The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression
  • Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
  • In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination
  • Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis
  • Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.