FEMA550658

UBA3 Recombinant Mouse Monoclonal Antibody (1B5-2-3-R), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550658-Each-of-1 In Stock ₹ 42,275.00

FEMA550658 - Each of 1

₹ 42,275.00

In Stock

Quantity

1

Base Price: ₹ 42,275.00

GST (18%): ₹ 7,609.50

Total Price: ₹ 49,884.50

Antigen

UBA3

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q8C878, Q8TBC4, Q99MI7

Gene Symbols

Uba3

Immunogen

Recombinant protein within Human UBA3 aa 220-424/463.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

1B5-2-3-R

Conjugate

Unconjugated

Gene

Uba3

Gene Alias

A830034N06Rik, AI256736, AI848246, AW546539, DKFZp566J164, hUBA3, MGC22384, NAE2, NEDD8-activating enzyme E1 catalytic subuni-like protein, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 subunit 2, NEDD8-activating enzyme E1C, Nedd8-activating enzyme hUba3, Uba3, UBA3, ubiquitin-activating enzyme E1 homolog, UBE1C, ubiquitin like modifier activating enzyme 3, ubiquitin-activating enzyme 3, Ubiquitin-activating enzyme E1C, ubiquitin-activating enzyme E1C (homologous to yeast UBA3), ubiquitin-activating enzyme E1C (UBA3 homolog, yeast), ubiquitin-like modifier activating enzyme 3, ubiquitin-like modifier-activating enzyme 3, Unknown (protein for MGC:140052), wu:fb75e04, wu:fc37b11, zgc:55528

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

117553, 22200, 9039

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • Positive control: HepG2 cell lysate, Hela cell lysate, 293T cell lysate, K-562 cell lysate, RAW264.7 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, human lung tissue lysate, human breast tissue, human esophagus tissue, human lung carcinoma tissue, human lung tissue, human skin tissue, SiHa
  • Predicted band size: 52 kDa Subcellular Location: Cytosol, nucleus, cytoplasm
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation
  • Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s
  • This gene encodes a member of the E1 ubiquitin-activating enzyme family
  • The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis
  • Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.