ZEB1 Recombinant Rabbit Monoclonal Antibody (JE57-64), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550808-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550808 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
ZEB1
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P37275
Gene Symbols
ZEB1
Immunogen
Recombinant protein within human ZEB1 aa 1-180/1124.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
JE57-64
Conjugate
Unconjugated
Gene
ZEB1
Gene Alias
[delta]EF1, 3110032K11Rik, AREB6, BZP, Delta EF1, delta-crystallin enhancer binding factor 1, deltaEF1, DELTA-EF1, FECD6, LOW QUALITY PROTEIN: zinc finger E-box-binding homeobox 1, MEB1, MGC133261, Negative regulator of IL2, Nil2, NIL2A, NIL-2A, NIL-2-A, NIL-2-A zinc finger protein, OTTHUMP00000019405, posterior polymorphous corneal dystrophy 3, PPCD3, RP11-472N13.4, Tcf18, TCF8, TCF-8, Transcription factor 8, transcription factor 8 (represses interleukin 2 expression), Tw, twirler, ZEB, Zeb1, Zfhep, Zfhx1a, Zfx1a, Zfx1ha, zinc finger E-box binding homeobox 1, zinc finger E-box-binding homeobox 1, Zinc finger homeobox protein 1a, zinc finger homeodomain enhancer-binding protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6935
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: Hela cell lysate, HUVEC cell lysate, human lung carcinoma tissue
- Predicted band size: 124 kDa Subcellular Location: Nucleus
- ZEB1 (Zinc finger E-box-binding homeobox 1) acts as a transcriptional repressor
- It inhibits interleukin-2 (IL-2) gene expression
- ZEB1 enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and depending on the cell type
- It represses E-cadherin promoters and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1
- ZEB1 also represses BCL6 transcription in the presence of the corepressor CTBP1
- It postively regulates neuronal differentiation and represses RCOR1 transcription activation during neurogenesis
- Mutations in the gene can result in corneal dystrophy, posterior polymorphous and corneal dystrophy, Fuchs endothelial 6.