FERMA549101

Viperin Monoclonal Antibody (MaP.VIP), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549101-Each-of-1 In Stock ₹ 56,248.00

FERMA549101 - Each of 1

₹ 56,248.00

In Stock

Quantity

1

Base Price: ₹ 56,248.00

GST (18%): ₹ 10,124.64

Total Price: ₹ 66,372.64

Antigen

Viperin

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.

Q8CBB9

Gene Symbols

Rsad2

Immunogen

Recombinant mouse viperin fragment (residues 92-362)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

MaP.VIP

Conjugate

Unconjugated

Gene

Rsad2

Gene Alias

2510004L01Rik; Best5; Bone-expressed sequence tag 5 protein; cig33; cig5; CIG6; cytomegalovirus-induced gene 5 protein; hypothetical protein LOC570456; inflammatory response gene 6 protein; inflammatory response protein 6; IRG6; radical S-adenosyl methionine domain containing 2; radical S-adenosyl methionine domain-containing protein 2; rsad2; rsad2 {ECO:0000250; si:ch211-276e8.2; similar to radical S-adenosyl methionine domain containing 2; UniProtKB:Q8WXG1}; VHSV-induced-like protein; Vig1; Viperin; viral hemorrhagic septicemia virus (VHSV)-induced gene 1; virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible; zgc:112342

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

58185

Content And Storage

4° C

Isotype

IgG2a

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Description

  • Viperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins
  • Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways
  • Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006)
  • Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011)
  • Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, )
  • Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies.