Desmin Monoclonal Antibody (DE-U-10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA122150-Each-of-1 | In Stock | ₹ 50,507.50 |
MA122150 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
Desmin
Classification
Monoclonal
Concentration
9.9 mg/mL
Formulation
Ascites with 15mM sodium azide
Gene Accession No.
O62654, P02540, P17661, P31001, P48675
Gene Symbols
DES
Immunogen
Purified, full length, native, pig desmin protein.
Regulatory Status
RUO
Gene ID (Entrez)
100328890, 100764990, 101097010, 101117308, 102180712, 13346, 1674, 280765, 396725, 64362
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
DE-U-10
Conjugate
Unconjugated
Gene
DES
Gene Alias
CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Feline, Goat, Hamster, Human, Multi-species, Mouse, Ovine, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Recommended positive controls: chicken gizzard
- Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle)
- Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation
- In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk
- The expression pattern of desmin in smooth muscle is much more heterogenous
- Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e
- rhabdomyosarcomas and leiomyosarcomas
- Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.