MA3-745
Vimentin Monoclonal Antibody (J144), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3-745-Each-of-1 | In Stock | ₹ 54,557.00 |
MA3-745 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,557.00
GST (18%): ₹ 9,820.26
Total Price: ₹ 64,377.26
Antigen
Vimentin
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.05% sodium azide
Gene Accession No.
P08670, P20152, P31000
Gene Symbols
Vim
Immunogen
Human rhabdosarcoma cell line JR1.
Regulatory Status
RUO
Gene ID (Entrez)
22352, 477991, 7431, 81818
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
J144
Conjugate
Unconjugated
Gene
Vim
Gene Alias
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species
Mouse
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgM
Related Products
Description
- MA3-745 detects human, rat, and mouse vimentin and has been successfully used in HELA-S3, HEK-293, rat brain, and rat kidney cells
- MA3-745 has been successfully used in Western blot, immunohistochemical and immunofluorescence procedures
- By Western blot, this antibody detects an ∽57 kDa protein representing vimentin from HELA-S3 cells
- Immunohistochemical staining of vimentin using MA3-745 can be performed
- The MA3-745 immunogen was human rhabdosarcoma cell line JR1
- Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
- It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
- Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
- During the development process, vimentin is exchanged for new, tissue-specific IFPs
- Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
- Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
- This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.