MA146057
HPV Type 16/18 E6 Monoclonal Antibody (C1P5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA146057-Each-of-1 | In Stock | ₹ 50,062.50 |
MA146057 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
HPV Type 16/18 E6
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
C1P5
Conjugate
Unconjugated
Gene Alias
HPV16; HPV-16; HPV18; HPV-18; human papillomavirus
Immunogen
Gel-purified HPV-18 E6-beta galactosidase fusion protein.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Human Papilloma virus (HPV) is responsible for the development of type and tissue specific papilloma in the oral cavity and in the larynx
- In the skin papilloma virus can cause different types of warts and in the ano-genital region it is associated with condyloma or carcinoma
- HPV types 1, 6 and 11 usually are associated with benign transformations of the tissues, while e.g
- HPV types 16, 18 and 31 seem to be responsible for the development of some carcinoma like cervical carcinoma
- The role of HPV in non-melanoic tumours of the skin is under discussion
- Protein E6 is a Transcriptional transactivator, binding double stranded DNA
- It has transforming activity inactivating, with E6-AP ubiquitin-protein ligase, the human TP53/p53 tumor suppressor protein by targeting it for degradation
- Clinical relevance: Detection of HPV in cervical smears and biopsies
- Uses: Analysis of E6 expression in cell transformation studies.