MA106310

Cardiotin Monoclonal Antibody (SR-4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA106310-Each-of-1 In Stock ₹ 47,481.50

MA106310 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

Cardiotin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Immunogen

Cardiotin purified from mouse spleen cells.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Frozen), Western Blot

Clone

SR-4

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Target Species

Human, Porcine

Product Type

Antibody

Isotype

IgM

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Description

  • MA1-06310 detects cardiotin in human and porcine samples
  • MA1-06310 has sucessfully been used in Western blotting and immunohistochemistry
  • By Western blotting, it detects a ∽300 kDa protein representing cardiotin from
  • The MA1-06310 immunogen is cardiotin purified from mouse spleen cells
  • Cardiotin is a recently discovered, high molecular weight protein complex (∽300 kDa) located in the longitudinal SR of cardiomyocytes
  • The cardiotin complex exists as 60 kDa and 100 kDa subunits
  • Both subunits contain the same amino-terminal 14 amino-acid sequence, and show high homology to human skeletal muscle alpha-actin
  • The tetrameric configuration of the cardiotin protein complex suggests that it exists as a transmembrane complex with the N-terminus at the cytoplasmic side of the membrane, able to interact with actin
  • Immunofluorescence studies colocalize cardiotin with SERCA 2a ATPase in the longitudinal sarcoplasmic reticulum (SR), although cardiotin is not expressed in junctional SR with SERCA 2.