MA1843

NCoR2 Monoclonal Antibody (1542), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1843-Each-of-1 In Stock ₹ 44,188.50

MA1843 - Each of 1

₹ 44,188.50

In Stock

Quantity

1

Base Price: ₹ 44,188.50

GST (18%): ₹ 7,953.93

Total Price: ₹ 52,142.43

Antigen

NCoR2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

Q9Y618

Gene Symbols

NCOR2

Immunogen

Synthetic peptide corresponding to residues C G G A(2016) S A S D P H R E K T Q(2027) of human SMRT.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ChIP Assay, Immunohistochemistry, Western Blot

Clone

1542

Conjugate

Unconjugated

Gene

NCOR2

Gene Alias

CTG repeat protein 26; CTG26; N-CoR; NCOR2; N-CoR2; nuclear receptor corepressor; nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptors; silencing mediator of retinoic acid and thyroid hormone receptor; silencing mediator of retinoid acid and thyroid hormone receptor; SMAP270; SMRT; SMRTe; SMRTE-tau; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

9612

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-843 detects silencing mediator of retinoic acid & thyroid hormone receptor (SMRT) from human cells and tissues
  • MA1-843 has been successfully used in Western blotting and immunohistochemical procedures
  • By Western blot, this antibody detects ∽250 kDa and ∽220 kDa proteins representing endogenous levels of both known isoforms of SMRT in HeLa cell extracts
  • This antibody does not react with mouse tissue in Western blot applications
  • The MA1-843 immunogen is a synthetic peptide corresponding to residues C G G A(2016) S A S D P H R E K T Q(2027) of human SMRT
  • MA1-843 immunizing peptide (Cat
  • # PEP-043) is available for use in neutralization and control experiments
  • Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily
  • Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate
  • Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.