Mu-Calpain Monoclonal Antibody (2H2A7C2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3941-Each-of-1 | In Stock | ₹ 57,316.00 |
MA3941 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,316.00
GST (18%): ₹ 10,316.88
Total Price: ₹ 67,632.88
Antigen
Mu-Calpain
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.05% sodium azide
Gene Accession No.
P07384, P35750, P97571, Q27970
Gene Symbols
CAPN1
Immunogen
Purified bovine skeletal muscle 80 kDa mu-calpain subunit.
Regulatory Status
RUO
Gene ID (Entrez)
281661, 29153, 397027, 823
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Clone
2H2A7C2
Conjugate
Unconjugated
Gene
CAPN1
Gene Alias
calcium activated neutral protease; calcium-activated neutral protease 1; calcium-activated neutral proteinase 1; calcium-dependent protease; calpain; calpain 1; calpain 1 large subunit; calpain 1, (mu/I) large subunit; calpain 1, large subunit; calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP; CANP 1; Canp1; CANPL1; Capa1; Capa-1; Capn1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Cls1; I79_024883; micromolar calcium-activated neutral protease 1; micromolar calcium-activated neutral protease 1 isoform A; micromolar calcium-activated neutral protease 1 isoform B; micromolar calcium-dependent neutral protease large subunit; micromolar-calpain; mucalpain; mu-calpain; mu-calpin; muCANP; muCL; PIG30; SPG76
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Porcine, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA3-941 detects mu-calpain from human platelets and erythrocytes, bovine platelets, heart and skeletal muscle, rat myoblasts, kidney, liver and spleen, and pig cultured cells
- This antibody does not cross-react with m-calpain, n-calpain, calmodulin or calpastatin
- MA3-941 has been successfully used in Western blot, IF and immunocytochemistry procedures
- By Western blot, this antibody detects an ∽80 kDa protein representing mu-calpain from human platelets and erythrocytes
- Immunocytochemical staining of mu-calpain in porcine LLC-PK1 cells with MA3-941 results in diffuse cytoplasmic staining
- This product has not been shown to be effective in immunoprecipitation experiments
- The MA3-941 antigen is purified bovine skeletal muscle 80 kDa mu-calpain subunit
- This antibody recognizes an epitope between amino acids 245-265 (domain II) of human mu-calpain
- The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases
- The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins
- The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit
- This gene encodes the large subunit of the ubiquitous enzyme, calpain 1
- Several transcript variants encoding two different isoforms have been found for this gene
- Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.