MABE972MI
MilliporeSigma™ Mouse anti-PRDM5, Clone: 57-20,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE972MI-Each-of-1 | In Stock | ₹ 40,292.08 |
MABE972MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,292.08
GST (18%): ₹ 7,252.574
Total Price: ₹ 47,544.654
Antigen
PRDM5
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
PRDM5; PFM2
Immunogen
GST-tagged recombinant protein corresponding to human PRDM5 near the N-terminus.
Quantity
200 μg
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_061169
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2b κ
Applications
Immunoprecipitation, Western Blot
Clone
57-20
Gene Accession No.
Q9NQX1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse
Form
Purified
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Description
- Specifically detects PRDM5 clone: 57-20 in Mouse samples, and it is validated for Immunoprecipitation, Western Blotting PR domain zinc finger protein 5 (UniProt Q9NQX1) is encoded by the PRDM1 gene (also known as BCS2, PFM2) in human (Gene ID 11107)
- PRDM proteins constitute a family of transcriptional regulators that are characterized by the presence of variable numbers of zinc finger domains and an N-terminal PR domain
- PRDM5 can negatively regulate gene transcriptions by recruiting the G9a histone methyltransferase and histone deacetylases
- PRDM5 can promote transcription by targeting enhancer-like elements or recruiting RNA polymerase II binding
- PRDM5 is highly expressed in murine embryonic stem cells (mESCs) and associates with complexes involved in chromatin organization, such as Ctcf, Smc1 (cohesin), and TFIIIC, which indicates their involvement in chromatin organization
- PRDM5 is often found silenced in human breast, ovarian, liver, and cervical cancers.