MABE966MI
MilliporeSigma™ Mouse anti-DNA polymerase II subunit A, Clone: 9F11.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE966MI-Each-of-1 | In Stock | ₹ 37,825.00 |
MABE966MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,825.00
GST (18%): ₹ 6,808.50
Total Price: ₹ 44,633.50
Antigen
DNA polymerase II subunit A
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
POLE; POLE1
Immunogen
GST-tagged recombinant protein corresponding to human DNA polymerase II subunit A near the N-terminus.
Quantity
200 μg
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_006222
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
Western Blot
Clone
9F11.1
Gene Accession No.
Q07864
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
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Description
- Specifically detects DNA polymerase II subunit A clone: 9F11.1 in Human samples, and it is validated for Western Blotting DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7; UniProt Q07864; also known as DNA polymerase II subunit A) is encoded by the POLE (also known as CRCS12, FILS, POLE1) gene (Gene ID 5426) in human
- DNA polymerase II is one of the six known mammalian template-directed DNA polymerases
- It is composed of two subunits (261kDa and 59kDa)
- The larger catalytic subunit is a B-type polymerase family member, containing polymerase and intrinsic 3'-5' exonuclease activities in its N-terminal part and a putative zinc-finger domain in its C-terminus
- POLE gene mutations are linked to colorectal cancer, facial dysmorphism, immunodeficiency, livedo, and short stature.