MABN1587
MilliporeSigma™ Mouse anti-MATR3, Clone: 3G1.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN1587-Each-of-1 | In Stock | ₹ 31,862.00 |
MABN1587 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,862.00
GST (18%): ₹ 5,735.16
Total Price: ₹ 37,597.16
Antigen
MATR3
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
MATR3; ALS21; KIAA0723; VCPDM
Immunogen
GST-tagged recombinant internal fragment from the N-terminal half of human martin-3.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_001181884
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2b κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
3G1.1
Gene Accession No.
P43243
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Related Products
Description
- Specifically detects MATR3 clone: 3G1.1 in Human, Mouse samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Matrin-3 (UniProt P43243) is encoded by the MATR3 (also known as ALS21, KIAA0723, VCPDM) gene (Gene ID 9782) in human
- Matrin-3 is an inner nuclear matrix protein involved in multiple nuclear processes, including DNA double strand break response, DNA replication/repair, chromatin organization, and RNA stability and processing
- Matrin-3 contains two RNA recognition motifs (a.a
- 398-473/RRM1 and a.a
- 496-571/RRM2) that mediate RNA-binding and a DNA-binding zinc finger motif (a.a
- 801-832)
- Matrin-3 is known to interact with the RNA-binding protein TDP-43 and MATR3 gene mutations are linked to amyotrophic lateral sclerosis (ALS)
- Matrin-3 is also a known target of multiple alpha herpes viruses and is known to be utilized by HIV-1 as a Rev cofactor.