MABN364MI
MilliporeSigma™ Mouse anti-SNAP91, Clone: 7H12.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN364MI-Each-of-1 | In Stock | ₹ 40,292.08 |
MABN364MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,292.08
GST (18%): ₹ 7,252.574
Total Price: ₹ 47,544.654
Antigen
SNAP91
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgMκ antibody in buffer containing PBS with 0.05% sodium azide.
Gene Symbols
SNAP91; KIAA0656
Immunogen
Linear peptide corresponding to human SNAP91 near the C-terminus.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_001229721
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgM κ
Applications
Western Blot
Clone
7H12.1
Gene Accession No.
O60641
Host Species
Mouse
Purification Method
Purified by Ion-Exchange Chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects SNAP91 clone: 7H12.1 in Human, Mouse, Rat samples, and it is validated for Western Blotting Clathrin coat assembly protein AP180 (UniProt O60641), also known as Phosphoprotein F1-20, Assembly protein, 180kDa, 91kDa synaptosomal-associated protein, Clathrin coat-associated protein AP180, Synaptosomal-associated protein 91kDa homolog) is encoded by the SNAP91 gene in human
- Clathrin-mediated endocytosis (CME) is a regulated process for internalization of transmembrane cargo
- Clathrin molecules initially assemble into a vesicle coat at the plasma membrane, then a specific cargo sorting process selects and concentrates proteins into the newly formed vesicle
- CME mediates traffic to different target membranes for cargo delivery inside cells
- Both clathrin assembly and cargo sorting functions are controlled by SNAP91 protein (AP180) and its ubiquitously expressed homolog clathrin assembly lymphoid myeloid leukemia protein (CALM)
- AP180 mediates clathrin assembly with its C-terminal assembly domain, whose central acidic clathrin and adapter binding (CLAP) sub-domain contains all of the known short binding motifs for clathrin and the adapter complex, AP2
- The sequence of the remaining AP180 C-terminal sub-domain is conserved in CALM and functions to ensures efficient clathrin binding.