MABS519AF48
MilliporeSigma™ Mouse anti-P40, Clone: 11F12.1, Alexa Fluor 488,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS519AF48-Each-of-1 | In Stock | ₹ 40,291.19 |
MABS519AF48 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,291.19
GST (18%): ₹ 7,252.414
Total Price: ₹ 47,543.604
Antigen
P40
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Gene Accession No.
Q9H3D4
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Applications
Immunocytochemistry, Immunohistochemistry
Clone
11F12.1
Formulation
Purified mouse conjugate antibody in PBS with 15mg/mL BSA and 0.1% sodium azide.
Gene Symbols
TP63; KET; P63; P73H; P73L; TP73L
Immunogen
KLH-conjugated linear peptide corresponding to human P40 near the N-terminus.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_001108450
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Related Products
Description
- Specifically detects P40 clone: 11F12.1 in Human, Mouse samples, and it is validated for Immunocytochemistry, Immunohistochemistry Tumor protein 63 (UniProt Q9H3D4; also known as Amplified in squamous cell carcinoma, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p73L, TP63, Transformation-related protein 63, Tumor protein p73-like) is encoded by the TP63 (also known as KET, P63, P73H, P73L, TP73L) gene (Gene ID 8626) in human
- Tumor protein 63 is a p53 homologue that can bind p53-responsive elements to upregulate some p53 target genes and share partially overlapping functions with p53
- Various functions have been ascribed to TP63 in normal squamous epithelia, including those of the esophagus and TP63 is reported to play an essential role in the maintenance of proliferative potential in epithelial stem cells
- TP63 overexpression is found in various squamous epithelia carcinomas and high TP63 expression is associated with an aggressive phenotype and metastasis in many cancers.