FKBP5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1020-Each-of-1 | In Stock | ₹ 46,235.50 |
PA1020 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,235.50
GST (18%): ₹ 8,322.39
Total Price: ₹ 54,557.89
Antigen
FKBP5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FKBP5
Gene Alias
51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; AIG6; androgen-regulated protein 6; D17Ertd592e; Dit1; EC 5.2.1.8; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; FKBP prolyl isomerase 5; Fkbp5; FKBP-5; FKBP51; FKBP-51; FKBP54; HSP90-binding immunophilin; p54; peptidylprolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP5; PPIase; PPIase FKBP5; Ptg-10; rotamase; T-cell FK506-binding protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100760904, 14229, 2289, 361810, 481759
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
Q13451, Q64378
Gene Symbols
FKBP5
Immunogen
Synthetic peptide corresponding to the residues C(394) Q K K A K E H N E R D R R(407) of human FKBP51.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Canine, Hamster, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-020 detects FK506 binding protein 51 kDa (FKBP51) in canine, hamster, human, mouse and rat tissues
- PA1-020 has been successfully used in Western blot procedures
- By Western blot, this antibody detects an ∽51 kDa protein representing FKBP51 in HeLa cell lysate
- By Western blot PA1-020 also detects FKBP51 in whole tissue extracts from rat kidney and rat and mouse testes
- The PA1-020 immunogen is a synthetic peptide corresponding to the residues C(394) Q K K A K E H N E R D R R(407) of human FKBP51
- There is a single amino acid substitution (K396 to R396) in this domain between human and mouse FKBP51 protein
- PA1-020 immunizing peptide (Cat
- # PEP-078) is available for use in neutralization and control experiments
- FKBP5 is a member of the immunophilin protein family
- This family plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking
- FKBP5 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin
- It is thought to mediate calcineurin inhibition
- It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein
- The gene that encodes FKBP5 has been found to have multiple polyadenylation sites
- Alternative splicing results in multiple transcript variants.