eNOS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1037-Each-of-1 | In Stock | ₹ 50,285.00 |
PA1037 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,285.00
GST (18%): ₹ 9,051.30
Total Price: ₹ 59,336.30
Antigen
eNOS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NOS3
Gene Alias
2310065A03Rik; cNOS; Constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial nitric oxide synthase NOS3; endothelial NOS; eNos; e-NOS; nitric oxide synthase; nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS; NOS type III; Nos3; Nos-3; NOSIII; OTTHUMP00000213183
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18127, 24600, 287024, 397557, 403784, 4846
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P29473, P29474, P70313, Q28969, Q62600, Q9TUX8
Gene Symbols
NOS3
Immunogen
Synthetic peptide corresponding to residues S(1179) L Q E R Q L R G A V P W A F D(1194) of human eNOS.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Canine, Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-037 detects endothelial nitric oxide synthase (eNOS) from bovine, canine, human, mouse, porcine and rat tissues as well as recombinant protein
- This antibody does not detect human iNOS or rat nNOS
- PA1-037 has been successfully used in Western blot and immunohistochemistry (paraffin and frozen) procedures
- By Western blot, this antibody detects an ∽140 kDa protein representing eNOS from human endothelial cells
- By Western blot PA1-037 also detects eNOS in rat lung, brain, and canine cardiac microsomes
- Immunohistochemical staining of eNOS in human vascular endothelial cells with PA1-037 results in prominent staining of the epithelial cells
- The PA1-037 immunogen is a synthetic peptide corresponding to residues S(1179) L Q E R Q L R G A V P W A F D(1194) of human eNOS
- Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells
- Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
- NO production is mediated by members of the nitric oxide synthase (NOS) family
- NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
- Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
- All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains.