OGG1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA131402-Each-of-1 | In Stock | ₹ 53,845.00 |
PA131402 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,845.00
GST (18%): ₹ 9,692.10
Total Price: ₹ 63,537.10
Antigen
OGG1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
OGG1
Gene Alias
8-hydroxyguanine DNA glycosylase; 8-oxoguanine DNA glycosylase; 8-oxoguanine DNA-glycosylase 1; 8-oxoguanine-DNA-glycosylase; AP lyase; DNA-(apurinic or apyrimidinic site) lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; Mmh; MUTM; N-glycosylase/DNA lyase; OGG1; OGG1 type 1f; OGH1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18294, 4968, 81528
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O08760, O15527, O70249
Gene Symbols
OGG1
Immunogen
A peptide derived from human Ogg1 (within amino acids 1-100) (UniProt# O15527)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- 8-hydroxyguanine, a form of oxidative DNA damage induced by free radicals, causes G:C to T:A transversion
- In E
- Coli, three DNA repair enzymes exist to prevent the mutagenic effects of 8-hydroxyguanine
- One of these enzymes, MutM, was found to have a functional yeast (yOgg1) and human (hOgg1) homologue
- hOgg1 proteins efficiently released the 8-hydroxyguanine opposite the pyrimidine from DNA and cleaved the AP site in a manner similar to bacterial and yeast enzymes
- Genetic backgrounds in control of the repair of damaged DNA are involved in the susceptibility to cancer development
- The hOgg1 gene has been mapped to region 3p26
- 2, a region showing loss of heterozygosity (LOH) in a variety of cancers
- In particular, 3p25-p26 is a common LOH region in lung cancer.