Phospho-nNOS (Ser1417) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1032-Each-of-1 | In Stock | ₹ 50,107.00 |
PA1032 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,107.00
GST (18%): ₹ 9,019.26
Total Price: ₹ 59,126.26
Antigen
Phospho-nNOS (Ser1417)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NOS1
Gene Alias
2310005C01Rik; bNOS; bNOS1; Brain NOS; Constitutive NOS; IHPS1; NC-NOS; neuronal nitric oxide synthase; neuronal nitric oxide synthase NOS1; neuronal NOS; nitric oxidase synthase; nitric oxide synthase; nitric oxide synthase 1; nitric oxide synthase 1 (neuronal); nitric oxide synthase 1, neuronal; nitric oxide synthase, brain; nNOS; N-NOS; nNOS; NOS type I; NO; NOS; NOS Type 1; NOS type I; Nos1; Nos-1; NOS-I; Peptidyl-cysteine S-nitrosylase NOS1; Phospho-bNOS; Phospho-Brain NOS
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
24598, 4842
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P29475, P29476
Gene Symbols
NOS1
Immunogen
Synthetic phosphopeptide corresponding to residues C N(1411) R L R S E (pS) I A F I E E S K(1425) of human nNOS.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-032 detects phosphorylated nNOS (Ser 1417) from rat and human samples
- PA1-032 has been successfully used in Western blot and immunofluorescence procedures
- By Western blot, this antibody detects an ∽140 kDa protein representing recombinant rat phospho-nNOS (Ser 1417)
- The PA1-032 immunogen is a synthetic phosphopeptide to residues C N(1411) R L R S E (pS) I A F I E E S K(1425) of human nNOS
- The peptide sequence is 100% conserved in rat, frog, and mouse protein
- This peptide (Cat
- # PEP-188) is available for use in neutralization and control experiments
- NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme)
- Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes
- These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.