Perilipin A/B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA11052-Each-of-1 | In Stock | ₹ 44,544.50 |
PA11052 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,544.50
GST (18%): ₹ 8,018.01
Total Price: ₹ 52,562.51
Antigen
Perilipin A/B
Classification
Polyclonal
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P43883, P43884, Q8CGN5
Gene Symbols
Plin1, Plin2
Immunogen
Synthetic peptide corresponding to residues M(1) S M N K G P T L L D G D L P E Q(17) C of rat Perilipin A and B.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
Plin1
Gene Alias
6030432J05Rik; AA407157; ADFP; Adipophilin; adipose differentiation related protein; adipose differentiation-related protein; ADPH; ADRP; FPLD4; lipid droplet-associated protein; PERI; PERIA; perilipin 1; perilipin 2; perilipin A; perilipin B; perilipin-1; Perilipin-2; PLIN; PLIN1; Plin2
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
103968, 11520, 25629, 298199
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- PA1-1052 detects perilipin A and B from rat and 3T3-L1 cell extract
- PA1-1052 has been successfully used in Western blot procedures
- By Western blot, this antibody detects ∽62 and 46 kDa proteins representing perilipin A and B, respectively from 3T3-L1 cell extract The PA1-1052 immunogen is a synthetic peptide corresponding to residues M(1) S M N K G P T L L D G D L P E Q(17) C of rat Perilipin A and B
- This sequence is 82% conserved in humans
- The PA1-1052 immunizing peptide (Cat
- # PEP-170) is available for use in neutralization and control experiments
- Adipose tissue is an energy reserve in animals and is strictly regulated in nondomestic species
- Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), resistin, and perilipin
- Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated
- This protein is localized exclusively to the surface of lipid droplets
- In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A
- Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body
- Perilipin expression is limited to adipocytes and steroidogenic cells
- There are currently two known isoforms, Perilipin A and B
- Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.